intro

Discoveries And Patents


With plans to increase the resources necessary to foster growth within the internal discovery program, NeoCodex continues to build an impressive proprietary portfolio of scientific patents. Already holding title to over 10% of all the biotechnology patents issued throughout the Spanish region of Andalusia, NeoCodex remains successful in maintaining a progressive pipeline of novel genetic marker panels and analytic research tools.


  • Genetic Marker Patents



  • Male Infertility



    • Issued patent protection for the successful development of a novel methodology deemed useful in the detection of associations linking genetic variation with a predetermined risk for developing human idiopathic infertility; information of originality holds promise for facilitating advancements in both the diagnosis and prognosis of the disease.


      · Galan JJ, Rivero MC, Salinas A, Real LM, Royo JL, Ruiz A
      Método de Diagnóstico de predisposición a padecer infertilidad masculina idiopática
      NºRegistro: P200602692
      Fecha de Prioridad: 23/octubre/2006
      Entidad Titular NeoCodex SL
      Paises: España


      ABSTRACT


  • Polycystic Ovary Syndrome (PCOS) and Cardiovascular Risk



    • Presently issued three patents focused on the discovery of novel association and marker data for the calpain 5 genes; Neocodex continues to gather information on the genetic influences present in patients diagnosed with Polycystic Ovarian Syndrome. Providing detailed linkage data thought essential to advancing the case of genetic predisposition, in-vitro diagnosis, and the dissemination of a proposal suggesting shared genetic markers linking PCOS with predictive genetics factors of use in assessing cardiovascular risk factors.


      · Ruiz A; Ramírez-Lorca R; Galan JJ ; Saez ME ; Real LM
      Método y dispositivo de detección in vitro de patologías de riesgo cardiovascular
      NºRegistro: P200402737
      Fecha de prioridad : 15/Noviembre /2004
      Paises: España


      ABSTRACT


      · Ruiz A; Ramírez-Lorca R; Galan JJ ; Saez ME ; Real LM
      Método y dispositivo de detección in vitro del síndrome de ovario poliquístico (PCOS) y de patologías que suponen riesgo cardiovascular
      NºRegistro: PCT/ES2005/070073 y patente US
      Paises: PCT, EEUU


      ABSTRACT


  • Ovarian Function



    • Two additional patents have been issued detailing the identification of common genetic patterns displayed amongst women sharing the trait of abnormal ovarian function. These findings are expected to be significant in progressing understanding of ovarian function and menopausal age, in addition to providing insight on the positive association relating an increase of estrogen exposure to that of inflated risk for the perimenopausal diagnoses of diseases such as breast cancer, osteoporosis, depression and cardiovascular disease.


      · Morón FJ, Royo JL, Saez ME, Real LM, Ruiz A
      Método de detección in vitro de la predisposición a desarrollar alteraciones en la función ovárica
      NºRegistro: P200502225
      Fecha de Prioridad: 13/Septiembre/2005
      Entidad Titular: NEOCODEX SL
      Paises: Espaa


      ABSTRACT


  • Research Tool Patents




    • HFCC


    Based on an initial patent outlining the process of conducting "Hypothesis Free Clinical Cloning," the term 'HFCC' serves to describe the proprietary method used by NeoCodex to design, execute, and analyze the data produced by whole genome association studies. Revolutionary in its ability to circumvent the drawbacks commonly associated with genome-wide scans, HFCC allows for unparalleled success in identifying genetic associations and markers, through permitting the analysis of both single and multivariate traits.


      · Ruiz A
      Hypothesis free clinical Cloning, a new method to isolate genetic interactomes associated to common traits. (MÉTODO Y APARATO PARA DETERMINAR ASOCIACIONES GENÉTICAS)
      NºRegistro: 200600061
      Fecha de Prioridad: 11/Enero/2006
      Entidad Titular: NEOCODEX SL
      Paises: Espaa


      ABSTRACT


      · Ruiz A
      Hypothesis free clinical Cloning, a new method to isolate genetic interactomes associated to common traits.
      NºRegistro: PCT/EP2007/050264
      Fecha de Prioridad: 11/Enero/2006
      Entidad Titular: NEOCODEX SL
      Paises: PCT, EEUU


      ABSTRACT